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Promoting a continued and much-needed renaissance in biopharmaceutical manufacturing, this book covers the different strategies and assembles top-tier technology experts to address the challenges of antibody purification.

•�� �Updates existing topics and adds new ones that include purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing
•�� �Presents new and updated discussions of different purification technologies, focusing on how they can address the capacity crunch in antibody purification
•�� �Emphasizes antibodies and innovative chromatography methods for processing

• Sales Rank: #1403035 in Books
• Published on: 2017-04-03
• Original language: English
• Dimensions: 9.40" h x 1.60" w x 6.30" l,
• Binding: Hardcover
• 752 pages

From the Back Cover

Stay on the cutting edge of antibody purification with the insights of industry experts

Biopharmaceutical companies are under extreme pressure to develop robust and economical large-scale processes while consistently meeting regulatory standards for safety and purity. Unfortunately, while upstream productivity has increased in line with demand, downstream processing is mired in a technology crisis resulting in production bottlenecks. Antibody purification is sandwiched between fermentation and drug formulation, two areas that have traditionally received the lion's share of industry awareness as well as generous research funding and attention in the literature. As a result, improvements in purification technology are needed urgently to meet the challenges of increasing demands without sacrificing product quality.

The second edition of Process Scale Purification of Antibodies continues the legacy of its predecessor to offer scientists, researchers, and engineers an essential resource focused on best practices in manufacturing antibody drugs. It covers different antibody purification strategies, including new developments since the publication of the first edition, and an assembly of top-tier experts in these disparate technologies with the common aim of addressing problems in process-scale antibody purification.

Recognized for providing a fresh perspective on traditional chromatography as well as alternative technologies and unit operations, the first edition covered innovative developments in protein purification like smart membranes, bioaffinity mimetics as well as orthogonal, and integrated strategies. The revision updates these topics and also introduces platform concepts that have gained traction over the ensuing years—including the purification of antibodies produced in novel production systems, novel separation technologies, novel antibody formats and alternative scaffolds, and strategies for ton-scale manufacturing.

Process Scale Purification of Antibodies, therefore, consolidates the unique niche occupied by its predecessor and maintains interest in this neglected subject area by promoting the continued, much-needed renaissance in antibody purification.

About the Author

Uwe Gottschalk, PhD,is Chief Technology Officer at Lonza Pharma/Biotech, Switzerland. Previously, he served as Group Vice President at Sartorius Stedim Biotech (2004-2014) and in various development and manufacturing capacities at Bayer Health Care (1991–2004). Dr. Gottschalk received a doctorate in chemistry from the University of M�nster (Germany) for work on antibody-drug conjugates at the Cancer Research Campaign Laboratories in Nottingham (UK). He is Head Lecturer at the University of Duisburg-Essen, Germany, and has written extensively in the areas of industrial biotechnology and somatic gene therapy.

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• Sales Rank: #5802004 in Books
• Published on: 1981-11
• Ingredients: Example Ingredients
• Original language: English
• Number of items: 1
• Dimensions: 10.00" h x 6.75" w x 1.50" l,
• Binding: Hardcover
• 586 pages

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[N911.Ebook] PDF Download Noble Lessons: Words of Islamic Wisdom: Collection of Islamic Articles based on Quran and Hadith, by IqraSense

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This book includes a compilation of articles that cover a number of important topics that can help a Muslim believer in his or her daily life. In the light of Islamic guidance from the Quran, Hadith of Prophet Muhammad (sallallahu alaihi wa sallam – may peace and blessings of Allah be upon him), and the explanations of many renowned scholars, these articles can serve as a beacon of light guiding the reader on many life’s issues. These include topics on how to handle life’s challenges, putting one’s trust in Allah, Islamic morals and etiquette, matters related to Muslim marriage, personal relationships, and many others. The following provides a brief synopsis of the various chapters and their contents.

• Understanding and Handling Life’s Difficulties, and Calamities

• Keeping A Strong Faith During Tough Times

• Matters of the (Muslim) Heart

• Taking Stock of Our “Thinking” Abilities

• Aligning Our Time to Life’s Purpose and Priorities

• The Blessings of Gratitude and Shukr

• Correcting Others by Advising and Not Condemning

• Ridding Oneself of Jealousy, Hatred, and Resentment

• Not Losing Hope in the Du’as That we Make

• Managing the Pain and Pleasure of Relationships

• The Sin of Riya (showing off)

• The Islamic Etiquette of Dealing with People

• How to use “Tawakkul” in Relieving our Anxieties and Worries

• Balancing Between “Tawakkul” In Allah And Human Efforts

• The Urgency of Personal Change

• The Necessity of Ikhlas (Sincerity)

• Tips for Your “Muslim Marriage”

• Reinforcing Traits of Personal Excellence

• Islamic Morals and Etiquettes

• Living Islam within a Family (Home)

• Sales Rank: #1749540 in Books
• Published on: 2014-11-07
• Original language: English
• Number of items: 1
• Dimensions: 9.00" h x .38" w x 6.00" l, .51 pounds
• Binding: Paperback
• 166 pages

About the Author
IqraSense is an Islamic blog covering religion topics on Islam and other religious topics.

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1 of 1 people found the following review helpful.
Five Stars
By rose
I love this book. There's so much words of wisdom to learn from it. Subhanallah.

0 of 0 people found the following review helpful.
Excellent read for Muslims!
By San Juan
Excellent book, Masha'Allah! Well written English book. Contains information and quotes from the Qur'an and Hadith. Good reminder of how to live life on a daily basis. Good to read with the family! Defintely worth the money.

0 of 0 people found the following review helpful.
Useful Islamic Lessons
By Muslimah
Concise small lessons that cover a lot of areas of ones life. Great and easy read for the entire family.

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[B249.Ebook] Get Free Ebook The Rebounding Workshop, by Kevin Sivils

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Basketball coaches around the world are constantly looking for ways to improve their team's rebounding on both the offensive and defensive end of the court.

The Rebounding Workshop contains both drills and concepts designed to help improve your team's rebounding. Included are 40 drills that cover a wide range of techniques to be repeated until perfected and honed into habits. Areas covered include:

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-offensive rebounding
-defensive rebounding
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• Sales Rank: #160535 in eBooks
• Published on: 2013-07-28
• Released on: 2013-07-28
• Format: Kindle eBook

About the Author
A native of Louisiana, Kevin Sivils has been a coach and teacher for 25 years. In the course of his coaching career, he has been a head coach for 22 seasons while winning 464 career wins and garnering 8 Coach of the Year awards. A current resident of the state of Texas, Coach Sivils has also worked extensively in athletic administration and athletic event promotion. Interestingly enough for a basketball coach from the Southern United States, he is an ice hockey fan, having been introduced to the sport by his wife Lisa, a native of Michigan and a Detroit Red Wings fan. His other passions include the history of North American Railroads and dogs, of which he currently has three. He and his wife Lisa work with an Italian Greyhound rescue serving as foster parents for abused and neglected Italian Greyhounds until they are ready to be adopted.

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0 of 0 people found the following review helpful.
Every missed shot is a pass to you!
By Justin Levy
Rebounding is often an overlooked part of a basketball game but coaches know how important it can be. Coach Sivils provides some thoughts on rebounding generally the most important being emphasis. The heart of the book is the rebounding drills. The book provides drills covering technique, competition, team cooperation, the fast break and more. The drills are also wonderfully annotated with coaching points and areas of emphasis for each drill.

0 of 0 people found the following review helpful.
Get every rebound
By Amazon Customer
Get EVERY rebound. Pound that into the players' heads. There's a lot of great information in this. Every coach should read it, and I honestly think every player should read it. There's not any "single best way" to play basketball, but if you don't rebound, you basically can't win. There are incredibly rare exceptions to that, but you definitely can't win against quality opponents. Great book.

0 of 0 people found the following review helpful.
very thorough
By mick kanuckel
along with an old out of print rebounding manual entitled WAR ON THE BOARDS by George Raveling, this was atop choice.

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Explore the Geography, History and Culture of the Western Hemisphere Grade Level: 06 - 07 Authors: Heidi Hayes Jacobs; Michal L. LeVasseur; Brenda Randolph. ISBN-10: 0130630039 ISBN-13: 978-0130630032

• Sales Rank: #525934 in Books
• Published on: 2002-01-01
• Original language: English
• Number of items: 1
• Dimensions: 11.20" h x 1.00" w x 8.70" l,
• Binding: Hardcover

Features

• Geography
• History
• Culture

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[N666.Ebook] Ebook Probability and Random Processes: With Applications to Signal Processing and Communications, by Scott Miller, Donald Childers

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Miller and Childers have focused on creating a clear presentation of foundational concepts with specific applications to signal processing and communications, clearly the two areas of most interest to students and instructors in this course. It is aimed at graduate students as well as practicing engineers, and includes unique chapters on narrowband random processes and simulation techniques.

The appendices provide a refresher in such areas as linear algebra, set theory, random variables, and more. Probability and Random Processes also includes applications in digital communications, information theory, coding theory, image processing, speech analysis, synthesis and recognition, and other fields.

* Exceptional exposition and numerous worked out problems make the book extremely readable and accessible
* The authors connect the applications discussed in class to the textbook
* The new edition contains more real world signal processing and communications applications
* Includes an entire chapter devoted to simulation techniques

• Sales Rank: #1443641 in Books
• Published on: 2004-10-07
• Original language: English
• Number of items: 1
• Dimensions: 9.25" h x 7.75" w x 1.00" l, 2.25 pounds
• Binding: Hardcover
• 552 pages

Most helpful customer reviews

2 of 2 people found the following review helpful.
Excellent
By A Reader
This book is excellent. All topics are fully explained in a relaxed, conversational style. Many clear, fully worked examples supplement the reading. The topics are well organized. There is a definite "and here is where this is used in practice" and "here is the important concept to remember" tone throughout the book that is very helpful. I highly recommend this text to both students and those who are learning on their own.

0 of 0 people found the following review helpful.
Excellent book
By CK
I have been reading about spectral estimation lately and accidentally found this book. I looked through the rest of the book which looks quite reader friendly but really got me was chapter 10 on Power Spectral density. This seemingly simple subject is really quite confusing what with deterministic signals, random ones, periodogram and correlogram and then many variants both parametric and non-parametric. They derive an equivalence between the periodogram and the correlation method showing exactly when that is so. The authors do a superb job, the best I have seen on the topic. Very impressive book.
Charan Langton - complextoreal.com

4 of 10 people found the following review helpful.
Not recommended
By K. Andringa
This is one of the worst texts I've had to use in my 6 years of engineering education. There are almost no relevant examples in this book and the homework problems stray far from the material in the text. Many fundamental steps are glossed over or skipped, leaving the student without the intuition to solve problems that stray from the norm.

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[B492.Ebook] Download The Last Call, by Charles Finney

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Biblical revival . . . and how you can have it!

Over one hundred years ago, God raised up a mighty man named Charles G. Finney. Because of God's power in his life, Finney's piercing words penetrated to the hearts of God's people. Many Christians were shocked and angered, but many heeded his message. As a result, sleeping churches were awakened and a powerful biblical revival swept over the land.

Today, we need this type of revival more than ever. To have it, we must follow the same time-tested methods used by Finney long ago. This enlightening book combines the burning words of Charles Finney with the irresistible cartoon art of Jack Chick to drive home many critical truths that are vital to all who long to experience true revival in their Christian life.

May the Lord use it to spark a flaming revival, first in your own heart and life, and then in the lives of those around you.

• Sales Rank: #515009 in eBooks
• Published on: 2012-01-04
• Released on: 2012-01-04
• Format: Kindle eBook

Review

"One hundred years ago, God raised up a voice so cutting, that it penetrated the hardened hearts of the sleeping Churches. The Christians were shocked and angered by such piercing words. God was crushing the believers by the voice of Charles G. Finney and a tremendous revival swept over the land. Today there is no voice strong enough to awaken the sleeping Christians and the end time is here. The Lord has placed on my heart to bring before the believers some of Finney's burning words." --Jack T. Chick - Author

From the Publisher
Now in affordable paperback, with enlarged text for easier reading!

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26 of 33 people found the following review helpful.
The truth shall set you free...
By A Customer
Unless your mind is open to considering the truth about modern christianity, I would not recommend reading it. This book is an excellent source of all the similarities between the christian and pagan festivals, symbolisms and dogmas. If one has a hard time accepting the facts presented in this book, one merely needs to converse with someone who practices paganism to validate its premise and conclusion. I suggest talking to wiccans about the spring and fall festivals. Even a quick glance at an ecyclopedia will reveal how pagan All Saints and All Souls days are, not to mention Halloween. I find that this book does not delve too deeply into the reasons and hisory surrounding the embracemant of pagan theology by the christian church. For these studies, I reccomend reading Primitave Christianity by Rudolph Bultmann, the Rise and Fall of the Roman Empire, or simply attending a college course on medieval european history or history of art. The most shocking thing I have found through my own investigation is that people who attend seminary or religious studies for the purpose of becoming a member of the clergy know all about these facts, but choose to ignore them and not teach then based on their blind faith. I have known such people who have left the clergy or gave up on the church because of what they learned in their studies. It is not difficult to confirm the premise and conclusion of this book with a little independent investigation.

0 of 0 people found the following review helpful.
Recommended for anyone serious about seeing revival come to America
By Rapurdy
This is a book that contains mostly of writings by Charles Finney. There is some good practical suggestions regarding revival and how to organize a prayer meeting. I gave it four stars because, while it is good reading with its comic book style inserts, and is recommended for anyone serious about revival in America, it was done with the style that failed to "grip my soul," although I KNOW we need revival in the worst way.

11 of 17 people found the following review helpful.
UNVEILING MYSTERY BABYLON
By A Customer
THIS A VERY INFORMATIVE BOOK ON THE ORIGIN OF THE MYSTERIOUS CULT OF BABYLON, AND THE EVOLUTION OF IT INTO THE PSUEDO-CHRISIAN WOMAN THAT WILL ULTIMATELY RIDE THE BEAST.A MUST READ FOR ANYONE SEKING TO UNDERSTAND THE HISTORY OF THE ORIGIN OF MANY OF TODAYS CHURCH TRADITIONS,ESPECIALLY THOSE OF ROMAN CATHOLIC ORIGIN. I BELIEVE THAT MR. HISLOP EXPOSES THE FRAUD OF CONSTANTINIAN CHRISTIANITY, BOTH PAST AND PRESENT.THE RESEARCH IN THIS TEXT IS EXTENSIVE AND IT IS ALSO A LITTLE WORDY FOR THOSE LESS TECHNICALLY INCLINED,BUT A GOOD READ NON THE LESS. I GIVE IT TWO THUMBS UP.

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[Z605.Ebook] Download Storage Implementation in vSphere 5.0 (VMware Press), by Mostafa Khalil

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THE ONLY AUTHORITATIVE, COMPREHENSIVE GUIDE TO VSPHERE STORAGE IMPLEMENTATION AND MANAGEMENT � Effective VMware virtualization storage planning and management has become crucial–but it can be extremely complex. Now, the leading VMware expert on storage completely demystifies the "black box" of vSphere storage and provides illustrated, step-by-step procedures for performing every key task associated with it. You’ll gain the deep understanding you need to make better storage decisions, solve problems, and keep problems from occurring in the first place. � Mostafa Khalil presents techniques based on years of personal experience helping customers troubleshoot storage in their vSphere production environments. With more experience than anyone else in the field, he combines expert guidelines, insights for better architectural design, best practices for both planning and management, common configuration details, and deep dives into both vSphere and third-party storage. � Storage Implementation in vSphere� 5.0 fully explains each storage connectivity choice and protocol supported by VMware, introduces Pluggable Storage Architecture (PSA), and shows how to build on PSA with multipathing, failover, and ALUA. It thoroughly introduces Storage Virtualization Devices (SVDs) and VMDirectPath I/O, and shows how to drive powerful improvements in performance, flexibility, and manageability with VMFS 5 and VAAI. � COVERAGE INCLUDES � Understanding how FC, FCoE, and iSCSI interact with VMware vSphere 5 Implementing specific VMware capabilities on storage hardware from each leading vendor Avoiding, recognizing, and fixing misconfigurations and other problems Using third-party MPIO plug-ins certified with vSphere 5 and PSA Maximizing availability through multipathing and failover Implementing fixed and round-robin multipathing on arrays with ALUA support Monitoring and optimizing virtual storage performance Managing vSphere-compatible file systems: VMFS and NFS Taking full advantage of VMDirectPath I/O Implementing heterogeneous storage configurations Presenting abstracted storage through virtual disks and Raw Device Mappings (RDMs) Using VMFS 5 to simplify management and improve scalability in large-scale environments Sharing storage and migrating more easily across multiple VMware vSphere instances Optimizing storage performance with VAAI-compliant devices Mostafa Khalil, Senior Staff Engineer with VMware Global Support Services, specializes in storage integration for virtual environments. He has worked for VMware for 13 years and supported all VMware virtualization products since Workstation for Linux 1.0 beta. Khalil has worked on most enterprise storage vendors’ solutions and received engineering-level training for many of them. He has presented at every VMworld, and at VMware Partner Exchange, VMware User Group, and USENIX. � � ISBN-13: 978-0-321-79993-7 ISBN-10: 0-321-79993-3

• Sales Rank: #868116 in eBooks
• Brand: Compaq
• Published on: 2012-08-23
• Released on: 2012-08-23
• Format: Kindle eBook

Features

• HP Emulex LightPulse LPe1205-HP Fibre Channel Host Bus Adapter - 2 x - PCI Express - 8Gbps

About the Author

Mostafa Khalil is a senior staff engineer at VMware. He is a senior member of VMware Global Support Services and has worked for VMware for more than 13 years. Prior to joining VMware, he worked at Lotus/IBM. A native of Egypt, Mostafa graduated from the Al-Azhar University’s School of Medicine, and practiced medicine in Cairo. He became intrigued by the mini computer system used in his medical practice and began to educate himself about computing and networking technologies. After moving to the United States, Mostafa continued to focus on computing and acquired several professional certifications. He is certified as VCDX (3, 4, & 5), VCAP (4 & 5)-DCD, VCAP4-DCA, VCP (2, 3, 4, & 5), MCSE, Master CNE, HP ASE, IBM CSE, and Lotus CLP. As storage became a central element in the virtualization environment, Mostafa became an expert in this field and delivered several seminars and troubleshooting workshops at various VMware public events in the United States and around the world.

Most helpful customer reviews

7 of 7 people found the following review helpful.
Incredibly Detailed Storage Information
By Chris Wahl
The book is filled with a treasure trove of historical knowledge that includes not only how storage (both as an industry and as it relates to VMware) evolved to what it is today, but why it evolved the way it did. You'll learn all about the VMFS file system and how to take advantage of it for all sorts of protocols and environments in both design and troubleshooting. This is simply a MUST HAVE book for anyone doing shared storage in VMware virtual environments as both reference material and a design aid, and will continue to be relevant long past the release of future vSphere 5.X products.

3 of 3 people found the following review helpful.
This book has it all!
By J. T. Schreiner
This is the storage book that I have been waiting for! Being relatively new to Storage/DataCenter, I've frustrated with with every other book and whitepaper because they either assume you are able to place things in context, or don't go into enough detail. This book satisfied all of my complaints with other materials. The author does an excellent job starting out with the context (and in some cases history behind how we got here in the first place) and delving into the material. I really like how the topics are covered from all different angles, the author showed us how we should accomplish tasks with the GUI and command line. It was very important to me that both were covered. It was also great the author included small bits of the storage vendor's material as well. Learning the VMWare part is important, and the focus of the book, but without the other side (storage vendor) you don't have the full picture. I was mainly looking for iSCSI info (which there was plenty of) but I ended up taking away a lot more useful knowledge. Like all the other reviewers, I consider this the definitive vSphere 5 storage book and would highly recommend anyone dealing with vSphere and SAN/NAS purchase this immediately.

3 of 3 people found the following review helpful.
Good book for block-based information
By Todd
This book contains extremely detailed information about block storage as it relates to vSphere. If you're running an environment consisting of FC, FCoE or iSCSI, this book will come in handy in endless ways.

However...

If you're looking for information regarding the implementation, design or inner workings of file-based (NFS) storage as it relates to vSphere, this is where the book falls flat. There is a smattering of info on how to work with VAAI primitives for NFS, but beyond that, the entire subject of NFS-based storage is barely mentioned at all. If you are looking for a book to help you understand the inner workings of the file-based datastore and how that works in relation to vSphere, keep looking.

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